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Related Concept Videos

Appendicitis01:19

Appendicitis

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Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
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Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

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The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
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Cholecystitis01:20

Cholecystitis

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Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
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Appendicitis-II: Diagnostic Studies and Management01:29

Appendicitis-II: Diagnostic Studies and Management

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Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
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Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
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Acute Pancreatitis I: Introduction01:25

Acute Pancreatitis I: Introduction

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Acute pancreatitis is the sudden inflammation of the pancreas caused by the early activation of digestive enzymes, leading to the autodigestion of pancreatic tissue. This results in local inflammation and, in severe cases, systemic complications.EtiologyUnderstanding the underlying causes is crucial, as identifying the etiology guides treatment and anticipates complications. Acute pancreatitis can be triggered by various factors, typically grouped into the following clinical categories.Biliary...
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Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
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[Schistosomiasis and acute appendicitis].

Jacinta Figueiredo1, Ângela Santos2, Horácio Clemente2

  • 1Serviço de Urologia. Hospital Américo Boavida. Luanda. Angola.

Acta Medica Portuguesa
|July 15, 2014
PubMed
Summary
This summary is machine-generated.

Schistosoma haematobium and Schistosoma mansoni infections are linked to acute appendicitis in Luanda. Histological analysis of appendectomy specimens revealed parasite eggs, suggesting a potential link between schistosomiasis and appendicular pathology.

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Area of Science:

  • Medical Parasitology
  • Gastrointestinal Pathology
  • Infectious Diseases

Background:

  • Schistosomiasis, a parasitic disease caused by blood flukes like Schistosoma haematobium and Schistosoma mansoni, is prevalent in Angola.
  • Acute appendicitis is a common surgical emergency.
  • The co-occurrence of schistosomiasis and appendicitis requires further investigation, especially in endemic regions.

Observation:

  • Two clinical cases of acute appendicitis were identified in patients undergoing urgent appendectomy.
  • Histological examination of surgical appendix specimens from these patients revealed the presence of Schistosoma haematobium and Schistosoma mansoni eggs.
  • Both patients resided in areas endemic for schistosomiasis and had childhood exposure to the parasite.

Findings:

  • The study identified a correlation between Schistosoma infection and acute appendicitis.
  • Presence of Schistosoma eggs in appendiceal tissues indicates a direct link between the parasite and appendicular pathology.
  • Chronic exposure to Schistosoma parasites, starting in childhood, may contribute to appendicular disease.

Implications:

  • These findings suggest that schistosomiasis may be an underdiagnosed cause of appendicitis in endemic areas.
  • Increased awareness among surgeons and pathologists is crucial for identifying concurrent cases of appendicitis and schistosomiasis.
  • This research highlights the need for considering parasitic infections in the differential diagnosis of abdominal conditions.