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Updated: Apr 27, 2026

Luminescence Lifetime Imaging of O2 with a Frequency-Domain-Based Camera System
Published on: December 16, 2019
An activatable, polarity dependent, dual-luminescent imaging agent with a long luminescence lifetime
Marcus T M Rood1, Maria Oikonomou, Tessa Buckle
1Interventional Molecular Imaging Laboratory, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands. f.w.b.van_leeuwen@lumc.nl.
Abstract:
In this proof-of-concept study, a new activatable imaging agent based on two luminophores and two different quenching mechanisms is reported. Both partial and total activation of the luminescence signal can be achieved, either in solution or in vitro. Bond cleavage makes the compound suitable for luminescence lifetime imaging.
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