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Updated: Apr 27, 2026
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Published on: January 12, 2022
Purtscher-like Retinopathy Associated with Systemic Lupus Erythematosus
Paradee Kunavisarut1, Kessara Pathanapitoon1, Aniki Rothova2
1a Department of Ophthalmology , Faculty of Medicine, Chiang Mai University , Chiang Mai , Thailand and.
Purpose:
To report on clinical manifestations of Purtscher-like retinopathy (PLR) associated with systemic lupus erythematosus (SLE) and visual outcomes.
Methods:
We performed a retrospective cohort study of 11 patients (21 affected eyes) with PLR in SLE.
Results:
All patients were treated with systemic corticosteroids ± immunosuppressive agents. Ocular therapy included intravitreal injections with bevacizumab in 18/21 eyes and posterior sub-Tenon injections with triamcinolone acetonide 13/21 eyes. Panretinal photocoagulation (PRP) was performed in 19/21 eyes and pars plana vitrectomy was required in 5/21 eyes. Visual improvement was found at follow-up of 3 and 6 months (p = 0.05). Poor visual outcome was associated with presence of neovascularizations at onset (p = 0.009), development of vitreous hemorrhage during PRP (p = 0.015), and active status of SLE after onset of PLR (p = 0.029).
Conclusions:
PLR might manifest as a devastating complication of SLE. We recommend treating any systemic activity of SLE and starting an early ocular treatment.
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