[Development of an ultrasonic system for the recanalization of coronary arteries]

We have devised an electro-acoustic system for the production and propagation of ultrasounds. With this system, linear vibrations can be transmitted through guides that are routinely used for coronary dilatation. Experiments performed on anatomical specimens have shown that ultrasounds are effective in destroying atheromatous formations. In addition, we tested this effectiveness with a setting that modelled the use of this system on the coronary vessels in terms of prerequisites: presence of a carrying catheter, aqueous environment, attention to vascular sinuosities and protection of arterial walls. The biological safety of low-frequency ultrasounds was tested in vitro and in animals. In view of these preliminary results, the subsequent development of an electro-acoustic system to be used in man seems to be justified.