The major histocompatibility complex and diseases in farm animals

Breeding for genetic resistance to disease and development of veterinary vaccines are major stimuli for research of the major histocompatibility complex (MHC) in farm animals. Genetically determined resistance is an attractive preventive measure because it precludes veterinary services, and is consistent over generations. Also many infectious diseases in farm animals cannot be prevented by vaccination. In a recent seminar sponsored by the European Community, the MHC of farm animals was discussed, its association with diseases was assessed, and other means of selection for disease resistance were evaluated.