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Goal-oriented treatment of pulmonary arterial hypertension

Carlos Jardim1, Caio Julio Cesar Fernandes, Rogerio Souza

  • 1Pulmonary Circulation Unit, Pulmonary Division, Heart Institute, University of Sao Paulo Medical School, Sao Paulo, Brazil.

Current Opinion in Pulmonary Medicine
|July 16, 2014
PubMed
Abstract

Insights

Establishing goal-oriented therapy for pulmonary arterial hypertension (PAH) management is crucial. This approach optimizes treatment response and improves long-term survival by setting and reassessing therapeutic goals.

Area of Science:

  • Cardiology
  • Pulmonology
  • Pharmacology

Background:

  • Pulmonary arterial hypertension (PAH) management has advanced with targeted therapies and prognostic markers.
  • Optimizing treatment strategies is key to further improving patient survival.

Purpose of the Study:

  • To explore the rationale for implementing goal-oriented therapy in pulmonary arterial hypertension management.
  • To enhance treatment efficacy and patient outcomes in PAH.

Main Methods:

  • Review of current therapeutic strategies and prognostic markers in PAH.
  • Analysis of the potential benefits of a goal-oriented approach.

Main Results:

  • Targeted therapies and prognostic markers have significantly improved PAH survival.
  • Shifting treatment strategies to optimize response may be the next critical step.

Conclusions:

  • Routine incorporation of prespecified goals and regular reassessment is recommended for PAH management.
  • This strategy aims to maintain patients in a clinical and functional status associated with better long-term survival.

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