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Artificial enzymes with protein scaffolds: structural design and modification

Takashi Matsuo1, Shun Hirota1

  • 1Graduate School of Materials Science, Nara Institute of Science and Technology (NAIST), Ikoma, Nara 630-0192, Japan.

Bioorganic & Medicinal Chemistry
|July 16, 2014
PubMed
Summary

Advancements in biochemistry and bioinformatics allow the creation of artificial enzymes for organic synthesis. These protein scaffolds are engineered using genetic mutation and designed evolution for specific catalytic activities like oxidation and reduction.

Keywords:
Artificial enzymeBiocatalystC–C bond formation/cleavageOxidationReduction

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