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Updated: Apr 27, 2026

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
Treatment of acute pulmonary embolism: update on newer pharmacologic and interventional strategies
Francesco Pelliccia1, Michele Schiariti1, Claudio Terzano2
1Department of Heart and Great Vessels "Attilio Reale", Sapienza University, Viale del Policlinico 155, 00161 Rome, Italy.
Abstract:
Acute pulmonary embolism (PE) is a common complication in hospitalized patients, spanning multiple patient populations and crossing various therapeutic disciplines. Current treatment paradigm in patients with massive PE mandates prompt risk stratification with aggressive therapeutic strategies. With the advent of endovascular technologies, various catheter-based thrombectomy and thrombolytic devices are available to treat patients with massive or submassive PE. In this paper, a variety of newer treatment strategies for PE are analyzed, with special emphasis on various interventional treatment strategies. Clinical evidence for utilizing endovascular treatment modalities, based on our institutional experience as well as a literature review, is provided.
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