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Updated: Apr 26, 2026

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
Published on: May 7, 2019
The reliability of red flags in spinal cord compression
Nicholas Tobias Johannes Raison1, Wisam Alwan1, Amit Abbot1
1Department of Trauma and Orthopaedics, Ashford and St Peter's NHS Trust, London, England.
Red flag symptoms for spinal cord compression in acute low back pain patients had limited predictive value. Bowel/bladder dysfunction and saddle anesthesia were statistically significant but only marginally increased suspicion in the emergency department (ED).
Area of Science:
- Emergency Medicine
- Neurosurgery
- Radiology
Background:
- Acute low back pain is a frequent emergency department (ED) presentation.
- Most cases (95%) have benign causes, necessitating identification of serious conditions via red flags.
Purpose of the Study:
- To evaluate the effectiveness of red flag signs in the ED for detecting spinal cord and cauda equina compression.
Main Methods:
- Retrospective cohort study of 206 patients with acute back pain admitted from the ED.
- Assessed red flag symptoms against magnetic resonance imaging (MRI) findings for spinal cord or cauda equina compression.
Main Results:
- 15.5% of patients showed compression on MRI.
- Bowel/bladder dysfunction (LR 2.45) and saddle sensory disturbance (LR 2.11) were significant predictors.
- Combined symptoms yielded a likelihood ratio (LR) of 3.46, with low sensitivity but high specificity.
Conclusions:
- The studied red flags only slightly increase clinical suspicion for spinal cord or cauda equina compression.
- Current red flag criteria are insufficient for effective risk stratification in the ED setting for acute back pain.
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