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Change of serum inorganic phosphate complexes in diabetic ketoacidosis
A Szabo1, T Tulassay, A Korner
11st Department of Pediatrics, Semmelweis University Medical School, Budapest, Hungary.
Abstract:
The concentrations of serum inorganic phosphate complexes (HPO4(2-), H2PO4-, NaHPO4-, KHPO4-, CaHPO4 and MgHPO4) were studied during diabetic ketoacidosis. On admission to hospital the H2PO4- concentration was significantly increased, in comparison with well-controlled diabetics. After 12-24 h the concentration of all phosphate complexes decreased. At 72 h only the MgHPO4 concentration was decreased. These changes are related to acidosis, insulin therapy and tubular dysfunction.