Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

11.9K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
11.9K
Neuron Structure01:30

Neuron Structure

17.7K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
17.7K
Neuron Structure01:31

Neuron Structure

196.3K
Overview
196.3K
Glial Cells01:04

Glial Cells

75.1K
Overview
75.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Nonlinear Electrical Transport Unveils Fermi Surface Malleability in a Moiré Heterostructure.

Nano letters·2024
Same author

Navigating dermatological care: Experience with assisted teledermatology practice on e-Sanjeevani platform.

Journal of the European Academy of Dermatology and Venereology : JEADV·2024
Same author

Light-Chain Deposition Diseases of the CNS: Review of Pathogenesis, Imaging Features, and Radiographic Mimics.

AJNR. American journal of neuroradiology·2024
Same author

Fear of Coronavirus Disease 2019 among People with Epilepsy.

The Journal of the Association of Physicians of India·2024
Same author

Managing outbreak of community-onset paediatric impetigo in underserved areas of North India via teledermatology: A tertiary care centre's experience.

Indian journal of dermatology, venereology and leprology·2024
Same author

Meningioma: Molecular Updates from the 2021 World Health Organization Classification of CNS Tumors and Imaging Correlates.

AJNR. American journal of neuroradiology·2024

Related Experiment Video

Updated: Apr 26, 2026

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

13.8K

Astrocyte morphology is controlled by neuron-derived FGF.

Amit Agarwal1, Dwight E Bergles1

  • 1Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.

Neuron
|July 18, 2014
PubMed
Summary

Neurons control astrocyte growth in Drosophila by releasing fibroblast growth factors (FGFs). This discovery sheds light on neuron-astrocyte communication and its role in brain development.

More Related Videos

Study Glial Cell Heterogeneity Influence on Axon Growth Using a New Coculture Method
09:19

Study Glial Cell Heterogeneity Influence on Axon Growth Using a New Coculture Method

Published on: September 6, 2010

16.8K
Analysis of Astrocyte Territory Volume and Tiling in Thick Free-Floating Tissue Sections
10:53

Analysis of Astrocyte Territory Volume and Tiling in Thick Free-Floating Tissue Sections

Published on: April 20, 2022

3.4K

Related Experiment Videos

Last Updated: Apr 26, 2026

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

13.8K
Study Glial Cell Heterogeneity Influence on Axon Growth Using a New Coculture Method
09:19

Study Glial Cell Heterogeneity Influence on Axon Growth Using a New Coculture Method

Published on: September 6, 2010

16.8K
Analysis of Astrocyte Territory Volume and Tiling in Thick Free-Floating Tissue Sections
10:53

Analysis of Astrocyte Territory Volume and Tiling in Thick Free-Floating Tissue Sections

Published on: April 20, 2022

3.4K

Area of Science:

  • Neuroscience
  • Developmental Biology
  • Cell Biology

Background:

  • Astrocytes possess highly branched processes crucial for neuronal support and brain homeostasis.
  • The mechanisms regulating astrocyte process extension and complexity remain incompletely understood.

Purpose of the Study:

  • To investigate the molecular control of astrocyte process development in Drosophila.
  • To identify signaling pathways mediating neuron-astrocyte interactions during development.

Main Methods:

  • Utilized Drosophila melanogaster as a model organism.
  • Employed genetic screening and live imaging techniques.
  • Analyzed astrocyte morphology and process dynamics in response to genetic manipulations.

Main Results:

  • Demonstrated that neuronal fibroblast growth factor (FGF) signaling is essential for astrocyte process extension and elaboration.
  • Identified specific neuronal populations that release FGF to influence astrocyte development.
  • Showcased the direct impact of neuron-derived FGF on astrocyte morphology and coverage.

Conclusions:

  • Neuronal FGF release is a key regulator of astrocyte process development in Drosophila.
  • This study reveals a novel mechanism of neuron-astrocyte communication essential for circuit formation.
  • Findings provide insights into the coordinated development of glial and neuronal cells.