[Pulmonary benign metastasizing leiomyoma: a clinicopathological study of 5 cases]

Pulmonary benign metastasizing leiomyoma (PBML) is a rare and often to be misdiagnosed disease. In this study, we want to investigate the diseased of the clinicopathological characteristics, diagnosis, treatment and prognosis. The retrospective analysis were performed on the clinicopathological data of 5 patients with PBML. All 5 cases were female, mean age 46.8 years old, and were found with single nodule. One case was found with left kidney metastasis. Surgical procedures includes: VATS biopsy (3 cases), resection of superior lobe of left lung (1 case), resection of superior lobe of right lung and wedge resection of middle and inferior lobe of right lung (1 case). The residual nodules in lung were stable in all cases with followup 3-48 mo. PBML is dominated occurring in females with history of uterine leiomyoma, preferential to metastasize to lung, and surgery is the primary therapy. Since it is hormone dependent, hormonal therapy may be suggested in these patients.