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Published on: May 2, 2018
Tuberculosis infection causing intestinal perforations in 2 patients with systemic lupus erythematosus
Luis A González1, Carolina Muñoz, Mauricio Restrepo
1From the *Sección de Reumatología, Universidad de Antioquia, Hospital Universitario San Vicente Fundación; †Hospital Pablo Tobón Uribe; and ‡Sección de Inmunogenética, Universidad de Antioquia, Medellín, Colombia.
Abstract:
Patients with systemic lupus erythematosus (SLE) have a higher incidence rate of tuberculosis and a more frequent extrapulmonary involvement than the general population. We present 2 SLE patients who developed gastrointestinal tuberculosis complicated with intestinal perforation, a rare but serious complication that could be confused with lupus-associated intestinal vasculitis. Opportunistic infections such as tuberculosis must be suspected in SLE patients with abdominal symptoms on immunosuppressive therapy because its early recognition could prevent catastrophic complications such as intestinal perforation and subsequent peritonitis.
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