Related Experiment Video
Updated: Apr 26, 2026
Simple Continuous Glucose Monitoring in Freely Moving Mice
Published on: February 24, 2023
Feasibility and precision of subcutaneous continuous glucose monitoring in patients undergoing CABG surgery
Hansjörg Aust1, Gerhard Dinges1, Stefan Nardi-Hiebl1
1Phillips-University of Marburg, Marburg, Germany and McGill University, Montreal, Quebec, Canada.
Objectives:
To evaluate if subcutaneous continuous glucose monitoring (sCGM) is feasible in cardiac surgery and if reliable glucose values are reported under hypothermic extracorporeal circulation.
Design:
Feasibility trial.
Setting:
University hospital.
Participants:
Ten consecutive patients undergoing coronary artery bypass grafting.
Interventions:
Prior to surgery, during hypothermic extracorporeal bypass, and 48 hours postoperatively, arterial blood glucose samples were compared with sCGM every 30 minutes. Statistical analysis utilized Clarke's error grid and Bland-Altman plot.
Measurements And Main Results:
Three hundred fifty-one pairs of glucose measurements were recorded including 59 during hypothermic extracorporeal circulation. Agreement between these measurements was acceptable, with a regression line slope of 0.88 and an offset of 17.4 (p = 0.87). Error grid analysis indicated a safe margin of 99.1% within zone A (no clinical action needed) or zone B (values would not lead to inappropriate treatment). Only 0.9% were plotted in zone D (potentially dangerous failure). Measurements during hypothermic extracorporeal circulation were comparable. Correlation coefficient was 0.760. The offset regression line was more pronounced (50.9) with a flatter slope (0.640). Within the error grid all plot values were in zone A or B.
Conclusions:
sCGM compared with arterial blood gas glucose monitoring under hypothermic extracorporeal circulation appears to be feasible and reliable.
