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A family exhibiting the cis-AB genotype
D S Ford1, J A Condon, J Bacon
1National Blood Group Reference Laboratory, Commonwealth Serum Laboratories, Parkville, Victoria.
Pathology
|January 1, 1989
Abstract:
Studies on blood samples from a 30-year-old woman of Korean origin, her husband and children, showed the presence of the cis-AB genotype in the mother and one child. The cis-AB red cells showed abnormal reactions with both polyclonal and monoclonal anti-B reagents and an elevated level of H antigen. The serum contained weak anti-B that reacted with normal B antigen but not with that on cis-AB cells. Normal levels of A substance but reduced levels of B and H substances were present in the saliva. Conversely, the serum showed reduced A and normal B and H blood group transferase activity.