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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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'Upgrading' psoriasis responsibly.

Sandra Boehncke1, Wolf-Henning Boehncke

  • 1Department of Diabetology, Endocrinology, Hypertension and Nutrition, Geneva University Hospital, Geneva, Switzerland.

Experimental Dermatology
|July 22, 2014
PubMed
Summary
This summary is machine-generated.

Psoriasis research is advancing, shifting focus from treatment to comprehensive management of this systemic disease. New insights into its causes and safer drugs prompt a reevaluation of therapeutic strategies.

Keywords:
comorbiditymanagementpsoriasisscreeningtreatment

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Area of Science:

  • Dermatology and cutaneous biology
  • Systemic inflammation research

Background:

  • Psoriasis pathophysiology and genetics are increasingly understood.
  • Clinical view of psoriasis evolving to include comorbidities and systemic aspects.
  • Advancements in drug safety and efficacy are enabling new treatment paradigms.

Purpose of the Study:

  • To evaluate the shift from a limited 'therapeutic' approach to a broader 'management' strategy for psoriasis.
  • To discuss the implications of new understandings and treatments for psoriasis care.

Main Methods:

  • Review of current understanding of psoriasis pathophysiology and genetics.
  • Analysis of the evolving clinical perspective on psoriasis, including comorbidities.
  • Assessment of the impact of new pharmaceutical developments on treatment strategies.

Main Results:

  • Significant progress in understanding psoriasis has been achieved.
  • The clinical perspective is expanding to recognize psoriasis as a systemic disease.
  • Improved drug profiles encourage a move towards long-term management.

Conclusions:

  • The evolving understanding and treatment options for psoriasis warrant a transition from 'therapy' to comprehensive 'management'.
  • Psoriasis should be viewed and managed as a systemic condition with broader implications beyond skin manifestations.