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[Cognitive functions in patients with chronic heart failure]
Zhurnal Nevrologii I Psikhiatrii Imeni S.S. Korsakova
|July 22, 2014
Summary
Patients with chronic heart failure (CHF) often experience cognitive impairment, particularly those with systolic dysfunction. This impairment is linked to reduced heart function, not carotid artery stenosis.
Area of Science:
- Cardiology
- Neurology
- Cognitive Science
Context:
- Chronic heart failure (CHF) affects cardiac and potentially cognitive function.
- Precerebral artery stenosis is a known risk factor for cerebrovascular events.
- The interplay between CHF, cognitive function, and arterial stenosis requires further elucidation.
Purpose:
- To assess cognitive functions in patients with varying stages of CHF.
- To investigate the relationship between cognitive deficits and the degree of precerebral artery stenosis.
- To differentiate cognitive impairment patterns based on heart failure type (systolic vs. diastolic).
Summary:
- 148 CHF patients and 21 controls underwent neuropsychological testing and vascular assessments.
- CHF patients exhibited more frequent multifocal cognitive impairment compared to controls.
- Systolic heart failure patients showed worse performance in frontal lobe functions and executive domains than diastolic heart failure patients.
- Cognitive decline in CHF correlated with lower left ventricular ejection fraction and diastolic dysfunction, independent of carotid artery stenosis.
Impact:
- Highlights the high prevalence of cognitive impairment in CHF patients.
- Identifies specific cognitive deficits, particularly executive dysfunction, in systolic heart failure.
- Suggests cardiac function, not carotid stenosis, is a primary correlate of cognitive impairment in CHF.
- Informs clinical practice regarding the neurological consequences of heart failure.
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