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A Case of Transient, Isolated Cranial Nerve VI Palsy due to Skull Base Osteomyelitis

Brijesh Patel1, Anas Souqiyyeh1, Ammar Ali2

  • 1Department of Internal Medicine, Providence Hospital and Medical Center, 16001 W Nile Mile Road, Southfield, MI 48075, USA.

Case Reports in Infectious Diseases
|July 22, 2014
PubMed

Insights

Malignant otitis externa can lead to skull base osteomyelitis and cranial nerve palsies. This case highlights successful antibiotic treatment for isolated cranial nerve VI palsy caused by skull base osteomyelitis.

Area of Science:

  • Otolaryngology
  • Neurology
  • Infectious Diseases

Background:

  • Otitis externa is a common infection treated with topical antibiotics.
  • Progression to malignant otitis externa can occur with treatment failure.
  • Skull base osteomyelitis, a complication, typically presents with multiple cranial nerve palsies.

Purpose of the Study:

  • To report a rare case of isolated cranial nerve VI palsy.
  • To investigate the link between skull base osteomyelitis and isolated cranial nerve involvement.
  • To demonstrate the efficacy of antibiotic therapy in such cases.

Main Methods:

  • Case report of a 54-year-old female patient.
  • Clinical presentation and diagnostic evaluation for skull base osteomyelitis.
  • Treatment with antibiotic therapy.

Main Results:

  • The patient presented with left cranial nerve VI palsy.
  • Skull base osteomyelitis was diagnosed as the cause.
  • The condition responded well to antibiotic treatment.

Conclusions:

  • Isolated cranial nerve palsies can be a rare manifestation of skull base osteomyelitis.
  • Prompt diagnosis and appropriate antibiotic therapy are crucial for favorable outcomes.
  • This case underscores the importance of considering osteomyelitis in refractory otitis externa with neurological deficits.

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