Related Experiment Video
Updated: Apr 26, 2026

04:04
Lateral Molar Approach-Driven Transoral Endoscopic Procedure for Benign Infratemporal Fossa Tumor Resection
Published on: August 15, 2025
676
[Peripheral ossifying fibroma of maxilla]
Duygu Erdem1, Gökçe Aksoy Yıldırım
1Department of Otolaryngology, Bartın State Hospital, 74100 Bartın, Turkey. duygualtuntas@gmail.com.
Summary
Peripheral ossifying fibromas, a rare condition where bone tissue replaces fibrous tissue, can present as oral masses. This case study details a 64-year-old female with a long-standing ossifying fibroma of the maxilla.
Area of Science:
- Oral pathology
- Maxillofacial surgery
- Oncology
Background:
- Peripheral ossifying fibromas (POFs) are benign, rare jaw tumors.
- They are characterized by the replacement of bone with fibrous tissue and calcifications.
Observation:
- A 64-year-old female presented with a 10-year history of an oral mass.
- Physical examination revealed a 5x4 cm, well-defined, pedunculated mass on the anterior arch of the right maxilla.
Findings:
- Clinical, radiographic, and histopathological evaluations confirmed the diagnosis of an ossifying fibroma.
- The lesion demonstrated characteristic features of bone formation within a fibrous stroma.
Implications:
- This case highlights the importance of thorough clinical and diagnostic evaluation for persistent oral masses.
- Surgical excision is typically the primary treatment for ossifying fibromas.
- Understanding the presentation of rare oral pathologies is crucial for accurate diagnosis and management.
More Related Videos
Related Concept Videos
Bone Formation by Intramembranous Ossification
16.1K
Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
16.1K
Bone Remodeling and Repair
9.2K
9.2K
Compact Bone
22.3K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
22.3K
Bone Formation by Endochondral Ossification
14.5K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
14.5K
Bone Remodeling
34.3K
Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
34.3K
Osteoclasts in Bone Remodeling
3.8K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.8K

