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Whole-body PET/MRI of Pediatric Patients: The Details That Matter
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A 31-channel MR brain array coil compatible with positron emission tomography.

Christin Y Sander1,2, Boris Keil1, Daniel B Chonde1

  • 1Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, Massachusetts, USA.

Magnetic Resonance in Medicine
|July 22, 2014
PubMed
Summary

A new 31-channel PET-compatible brain coil reduces photon attenuation and scattering, significantly improving PET/MR imaging sensitivity without compromising MR signal-to-noise ratio (SNR). This innovation enhances hybrid imaging capabilities.

Keywords:
PET-optimized coilRF coil attenuationintegrated PET/MRmultichannel brain arraysimultaneous PET/MR

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Area of Science:

  • Medical Imaging
  • Biophysics
  • Radiological Sciences

Background:

  • Simultaneous PET/MR imaging is hindered by MR coil interference with PET photon detection.
  • MR coils placed within PET scanners cause attenuation and scattering, reducing sensitivity for both modalities.
  • Optimizing sensitivity for both PET and MR in hybrid systems remains a significant technical challenge.

Purpose of the Study:

  • To develop and evaluate a novel 31-channel MR coil designed for PET compatibility.
  • To minimize the detrimental effects of MR coil components on PET photon detection.
  • To enhance overall sensitivity and image quality in simultaneous PET/MR imaging.

Main Methods:

  • Component-level testing was conducted to assess tradeoffs between PET and MR performance.
  • Key design aspects studied included preamplifier positioning, coaxial cable size, coil trace characteristics, and housing materials.
  • The coil was optimized for PET performance while minimizing impact on MR signal-to-noise ratio (SNR) and evaluated for PET attenuation.

Main Results:

  • The 31-channel PET-compatible coil demonstrated a 190% average improvement in attenuation compared to conventional 32-channel arrays.
  • No loss in MR signal-to-noise ratio (SNR) was observed with the new coil design.
  • A 230% SNR improvement was achieved in cortical regions compared to an 8-channel PET-optimized array, with effective removal of PET artifacts after correction.

Conclusions:

  • The developed 31-channel PET-compatible coil significantly enhances sensitivity for PET/MR imaging.
  • This advancement facilitates improved image quality and opens avenues for new applications in hybrid imaging.
  • The design effectively addresses the primary barrier to optimal sensitivity in simultaneous PET/MR acquisition.