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[Analysis of ocular changes in children craniopharyngioma]
Liu Yang1, Fengjun Liu1, Yang Tang1
1Department of Ophthalmology, Beijing Tiantan Hospital, Capital Medical University, Beijing 100050, China.
Insights
Children with craniopharyngioma often experience vision loss. Visual acuity and visual field defects were more pronounced than optic disc damage in pediatric craniopharyngioma patients.
Area of Science:
- Ophthalmology
- Pediatric Oncology
- Neuro-oncology
Background:
- Craniopharyngioma is a common pediatric brain tumor.
- Ocular complications can significantly impact quality of life in affected children.
Purpose of the Study:
- To investigate the specific ocular changes associated with pediatric craniopharyngioma.
- To analyze the relationship between tumor characteristics and visual deficits.
Main Methods:
- Retrospective case series of 17 pediatric patients (34 eyes).
- Analysis of preoperative clinical data including visual acuity, visual fields, and optic disc status.
- Tumor size and location data were also reviewed.
Main Results:
- Visual acuity deficits were observed in 79.41% of eyes.
- Visual field defects occurred in 76.47% of eyes.
- Abnormal optic disc findings (edema, atrophy, pallor) were present in 44.12%.
Conclusions:
- Visual acuity decline and visual field defects are significant in pediatric craniopharyngioma.
- Optic disc damage appears less frequent or severe compared to visual acuity and field deficits.
Objective:
To analyze the characteristics of ocular changes in children craniopharyngioma.
Methods:
Retrospective case series study. The clinical data of 34 eyes from 17 patients with children craniopharyngioma treated at the affiliated Beijing Tiantan Hospital, Capital Medical University from September 2011 to May 2012 were collected. Records of preoperative clinical examinations including best corrected visual acuity (BCVA), visual field test, optic disc findings, size and location of the tumor were analyzed.
Results:
The age of the patients was from 5 to 14 years old [mean (10.29 ± 3.22) years] with the male/female ratio of 1.83: 1. The most affected age group was 8 to 12 years old. Deficits in BCVA occurred in 79.41% (27/34). Abnormal optic disc findings occurred in 44.12% which included optic disk edema 5.9% (2/34), atrophic changes of the optic nerve 32.35% (11/34) and pale optic disc 5.9% (2/34). Various visual field defects were 76.47% (26/34).
Conclusion:
Declines of visual acuities and defects of visual fields were more severe than optic disc damages in children patients with craniopharyngioma.
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