Related Experiment Videos
Calcinosis circumscripta associated with polydioxanone suture in two young dogs.
B M Kirby1, J S Knoll, P A Manley
1Department of Surgical Sciences, School of Veterinary Medicine, University of Wisconsin, Madison 53706.
Veterinary Surgery : VS
|May 1, 1989
Summary
Calcinosis circumscripta, a soft tissue mineralization, was found in two dogs linked to polydioxanone sutures. These chalky masses formed along surgical incision sites where the sutures were located.
Area of Science:
- Veterinary Pathology
- Surgical Complications
- Biomaterials Science
Background:
- Calcinosis circumscripta is a rare condition characterized by soft tissue mineralization.
- Suture materials are common in veterinary surgery, and their biocompatibility is crucial.
- Polydioxanone (PDS) is a synthetic absorbable suture known for its strength and prolonged absorption time.
Observation:
- Two young dogs presented with firm subcutaneous masses at previous surgical incision sites.
- Radiographs revealed soft tissue mineralization consistent with calcinosis circumscripta.
- Surgical excision exposed linear, chalky white nodular masses along the suture line.
Findings:
- Histological examination confirmed calcinosis circumscripta.
- Polydioxanone suture material was identified within the center of the mineralized nodules.
- The mineralization was directly associated with the presence of the polydioxanone sutures.
Implications:
- Polydioxanone suture material may be implicated in the pathogenesis of calcinosis circumscripta in dogs.
- This finding highlights a potential complication associated with polydioxanone use in veterinary surgery.
- Further research is warranted to understand the mechanism and prevalence of this association.