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Case for diagnosis.

Andréa Buosi Fabre1, Paola C Vieira da Rosa Passos1, Brunno Zeni de Lima1

  • 1Faculdade Evangélica do Paraná, Curitiba, PR, Brazil.

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Summary

Intravascular papillary endothelial hyperplasia (IPEH) is a benign vascular lesion. This case report details a successful surgical removal of an occipital IPEH in a young male, with no recurrence.

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Area of Science:

  • Vascular pathology
  • Dermatopathology
  • Surgical oncology

Background:

  • Intravascular papillary endothelial hyperplasia (IPEH) is a rare, benign vascular proliferation.
  • It often arises reactively secondary to vascular injury, thrombosis, or inflammation.
  • Distinguishing IPEH from malignant vascular tumors like angiosarcoma is clinically crucial.

Observation:

  • A 14-year-old male presented with a progressively growing, violet-red tumoral lesion on the occiput.
  • Clinical examination revealed a vascular lesion requiring further diagnostic workup.
  • Histopathological analysis confirmed the diagnosis of IPEH.

Findings:

  • Histopathology demonstrated endothelial cell proliferation characteristic of IPEH.
  • Key diagnostic features included the absence of significant cellular atypia and rare mitotic figures.
  • Complete surgical excision of the lesion was achieved.

Implications:

  • IPEH can mimic angiosarcoma clinically and histologically, necessitating careful differentiation.
  • Prompt and complete surgical resection ensures a favorable prognosis with no recurrence.
  • Understanding IPEH's benign nature guides appropriate management and reassures patients.