Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Microbial Biosensors01:17

Microbial Biosensors

88
Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...
88
Blood Studies for Cardiovascular System I: Cardiac Biomarkers01:20

Blood Studies for Cardiovascular System I: Cardiac Biomarkers

1.2K
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
1.2K
Equipments Used To Measure Blood Pressure01:30

Equipments Used To Measure Blood Pressure

3.4K
Direct Method
This invasive approach involves cannulating a peripheral artery. During each cardiac contraction, pressure generates mechanical motion within the catheter, transmitted through rigid, fluid-filled tubing to a transducer. This transducer converts mechanical motion into electrical signals displayed as waveforms on a monitor. An automatic flushing system prevents blood backflow. Due to the potential risk of unexpected arterial blood loss, this method is primarily used in intensive...
3.4K
Pulse rhythm01:30

Pulse rhythm

1.7K
Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac...
1.7K
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

1000
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
1000
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

750
Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
750

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Epitope-imprinted nanogels for high-performance mass-based detection of pathogenic viruses.

Biosensors & bioelectronics·2026
Same author

Hydrogel Microneedle Array-Based Transdermal Dressing System for Multiplexed Assessment and Intelligent Therapy of Chronic Wounds.

Small (Weinheim an der Bergstrasse, Germany)·2025
Same author

Optical bio/chemical sensors for vitamin B<sub>12</sub> analysis in food and pharmaceuticals: state of the art, challenges, and future outlooks.

Beilstein journal of nanotechnology·2025
Same author

Tyrosine-Capped Pt Nanozyme Functionalized with cDNA: An Innovative Sensor Designed for One-Step Detection of the miRNA-21 Biomarker.

ACS omega·2025
Same author

Sweet cherry stalks to nanocrystalline cellulose: Synthesis, characterization, and stabilization of insect oil/water Pickering emulsions.

Food chemistry·2025
Same author

Atomic-Level Engineering of Synthetic Receptors for Enhanced Virus Detection and Removal.

Advanced healthcare materials·2025

Related Experiment Video

Updated: Apr 26, 2026

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

5.9K

Cardiovascular disease detection using bio-sensing techniques.

Zeynep Altintas1, Wellington M Fakanya2, Ibtisam E Tothill1

  • 1Advanced Diagnostics and Sensors Group, Cranfield University, Cranfield, Bedfordshire MK43 0AL, UK.

Talanta
|July 26, 2014
PubMed
Summary

Cardiovascular disease (CVD) causes millions of deaths globally. Advanced biosensors offer rapid, accurate early detection of CVD biomarkers, improving diagnosis and prognosis.

Keywords:
BiomarkersBiosensorsCardiovascular disease (CVD)Heart disease

More Related Videos

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

39.9K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

1.2K

Related Experiment Videos

Last Updated: Apr 26, 2026

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum
09:23

Using Extraordinary Optical Transmission to Quantify Cardiac Biomarkers in Human Serum

Published on: December 13, 2017

5.9K
Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies
07:20

Dried Blood Spot Collection of Health Biomarkers to Maximize Participation in Population Studies

Published on: January 28, 2014

39.9K
Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease
06:16

Signal Acquisition, Score Interpretation, and Economics of a Non-Invasive Point-of-Care Test for Coronary Artery Disease

Published on: August 9, 2024

1.2K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Analytical Chemistry

Background:

  • Cardiovascular disease (CVD) remains a leading global cause of mortality, with heart disease and stroke claiming over 20 million lives by 2015.
  • Current understanding of CVD initiation, symptoms, and early detection is insufficient, contributing to high mortality rates.
  • Early detection and accurate diagnosis are crucial for reducing the risk of sudden death from CVD.

Purpose of the Study:

  • To review the classification of CVD.
  • To discuss biomarkers used in CVD diagnosis.
  • To summarize the application and recent advancements of biosensors in CVD detection.

Main Methods:

  • Review of current literature on cardiovascular disease classification and diagnosis.
  • Analysis of various biomarkers utilized for CVD detection.
  • Exploration of biosensor technology, including microfluidics and nanotechnology, for rapid CVD screening.
  • Discussion of lab-on-a-chip (LOC) devices integrating multiple assays.

Main Results:

  • Biosensors are revolutionizing CVD diagnosis by enabling rapid screening of disease biomarkers.
  • Advances in microfluidics and nanotechnology have led to faster, more accurate, and portable diagnostic devices.
  • Lab-on-a-chip (LOC) technology integrates multiple assays into a single, portable device, reducing analysis time.
  • Interdisciplinary research efforts are driving the development of sophisticated affinity-based detection systems.

Conclusions:

  • Biosensors represent a significant advancement in the early detection and prognosis of cardiovascular disease.
  • The integration of microfluidics and nanotechnology is key to developing next-generation, high-performance diagnostic tools.
  • Continued research in biosensor technology promises to further improve CVD management and reduce mortality rates.