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Aggressive primary thyroid lymphoma: imaging features of two elderly patients
Eu Hyun Kim1, Jee Young Kim1, Tae-Jung Kim2
1Department of Radiology, Yeouido St. Mary's hospital, The Catholic University College of Medicine, Seoul, Korea.
Ultrasonography (Seoul, Korea)
|August 11, 2016
Summary
We describe two elderly patients with aggressive thyroid lymphoma presenting as large masses invading nearby structures. Imaging showed features mimicking anaplastic carcinoma, highlighting the need for biopsy for accurate diagnosis.
Area of Science:
- Oncology
- Radiology
- Pathology
Background:
- Aggressive primary thyroid lymphoma is a rare malignancy.
- It can present as large, infiltrative thyroid masses.
- These masses can invade adjacent vital structures.
Purpose of the Study:
- To report the imaging features of aggressive primary thyroid lymphoma.
- To emphasize ultrasonographic findings in diagnosing this rare condition.
- To discuss differential diagnoses, particularly anaplastic carcinoma.
Main Methods:
- Case report of two elderly patients.
- Detailed analysis of imaging findings from ultrasonography and computed tomography.
- Histopathological diagnosis via biopsy.
Main Results:
- Both cases presented as large, infiltrative thyroid masses with extensive invasion.
- Ultrasonography showed irregular, heterogeneous, hypoechoic masses.
- Computed tomography revealed heterogeneously enhancing masses without calcification or hemorrhage.
- Histopathology confirmed lymphoma.
Conclusions:
- Aggressive primary thyroid lymphoma is rare and can mimic other thyroid cancers.
- Characteristic imaging features, especially ultrasonographic findings, are crucial for diagnosis.
- Distinguishing lymphoma from anaplastic carcinoma requires biopsy and histopathological confirmation.
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