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Updated: Apr 26, 2026
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DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
Published on: December 29, 2021
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Rapid engineering of versatile molecular logic gates using heterologous genetic transcriptional modules
1Centre for Synthetic and Systems Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JR, UK. Baojun.Wang@ed.ac.uk.
Chemical Communications (Cambridge, England)
|July 26, 2014
Abstract:
We designed and constructed versatile modular genetic logic gates in bacterial cells. These function as digital logic 1-input Buffer gate, 2-input and 3-input AND gates with one inverted input and integrate multiple chemical input signals in customised logic manners. Such rapidly engineered devices serve to achieve increased sensing signal selectivity.
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