Related Experiment Video
Updated: Apr 26, 2026
Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A new Mucocutaneous Activity Index for Behçet's disease
Gonca Mumcu1, Nevsun Inanc, Ali Taze
1Faculty of Health Sciences, Department of Health Management, Marmara University, Istanbul, Turkey. gonca.mumcu@gmail.com.
Objectives:
Patient-reported outcomes are increasingly accepted to be major domains in chronic disorders. The aim of this study was to develop a patient-derived disease activity index in Beh-çet's disease (BD).
Methods:
One hundred and seventy-seven BD patients (M/F: 69/108) were included in the study. Data were collected by clinical examination and a questionnaire regarding a Mucocutaneous Index (MI) with genital ulcer activity (GI), erythema nodosum activity (EI) and the composite index (CI) for oral ulcers, as subscales of it. Self-reported treatment evaluation was carried out as criterion validity. Patients whose symptoms completely disappeared or decreased significantly, were categorised as 'improved group', others were classified as 'non-improved group'.
Results:
Among the study group, 79.7% of the patients (n=141) were active, whereas 20.3% were inactive (n=36). Scores of CI, GI, EI and MI score were 0±0 in inactive ones, whereas scores were 5.65±2.36 for CI, 0.81±2.34 for GI, 0.91±2.35 for EI and 6.25±5.1 for MI in actives (p=0.000 for all). MI score was significantly higher in 'non-improved group' (65.5%) compared to 'improved group' (34.5%) (p<0.0001).
Conclusions:
The mucocutaneous activity index may help decision-making process for treatment strategies in BD patients.
