Effect of iterative reconstruction algorithms on peripheral MDCT angiography virtual histology plaque volumes: have
Vivek V Patil1, Lawrence N Tanenbaum1, Robert A Lookstein1
1Department of Radiology, Icahn School of Medicine at Mount Sinai, One Gustave Levy Place Box 1234, New York, NY 10029, USA.
Abstract:
Our objective was to compare plaque volumes of multidetector computed tomographic images reconstructed using adaptive statistical iterative reconstruction (ASIR), model-based iterative reconstruction (MBIR), and filtered back projection (FBP). We reviewed 25 patients for a total of 50 extremities imaged on the same scanner. Calcified plaque FBP volume (3468.2 ± 2634.8 mm(3)) was higher than ASIR (2548.1 ± 2166.5 mm(3)). Calcified plaque FBP volume was higher than MBIR (mean=2345.7 ± 1935.4 mm(3)). Our findings suggest that traditional FBP methods overestimate disease compared to newer reconstruction methods.
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