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Modulation of macrophages and response of CD117(+) cells of different localization after liver damage in mice
I G Danilova1, I A Kazakova, B G Yushkov
1Institute of Immunology and Physiology, Ural Division of the Russian Academy of Sciences, Moscow, Russia, ig-danilova@yandex.ru.
Bulletin of Experimental Biology and Medicine
|July 30, 2014
Abstract:
We studied the effects of stimulation of mononuclear phagocyte system on the state of CD117(+) hepatocytes of growth zone and CD117(+) hemopoietic stem cells after liver damage. Increased number of CD117(+) hepatocytes and enhanced expression of given antigen was revealed. CD117(+) hemopoietic stem cells respond to the impact by migration to the regenerating organ.
