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Related Experiment Video

Updated: Apr 26, 2026

Combining Reflectance Confocal Microscopy with Optical Coherence Tomography for Noninvasive Diagnosis of Skin Cancers via Image Acquisition
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Becker's Nevus Syndrome.

Sathyanarayana B Dasegowda1, Gb Basavaraj1, Kc Nischal1

  • 1Department of Dermatology, Adichunchanagiri Institute of Medical Sciences, BG Nagara, Karnataka, India.

Indian Journal of Dermatology
|July 30, 2014
PubMed
Summary

This case report details a rare presentation of bilateral Becker's nevus in a 15-year-old female, associated with numerous systemic abnormalities, highlighting the complexity of Becker's nevus syndrome.

Keywords:
Becker's nevusBecker's nevus syndromecollagen hamartoma

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Area of Science:

  • Dermatology
  • Clinical Genetics
  • Pathology

Background:

  • Becker's nevus is a benign hamartoma causing hyperpigmentation and hypertrichosis.
  • Becker's nevus syndrome links these skin findings with developmental and skeletal anomalies.

Purpose of the Study:

  • To report a unique case of bilateral Becker's nevus with extensive systemic manifestations.
  • To describe the clinical and histopathological findings in a patient with a complex presentation of Becker's nevus syndrome.

Main Methods:

  • Clinical case presentation and detailed patient history.
  • Physical examination documenting dermatological and systemic abnormalities.
  • Histopathological analysis of the affected skin tissue.

Main Results:

  • A 15-year-old female presented with bilateral Becker's nevi and a constellation of symptoms including intellectual disability, developmental delay, dwarfism, skeletal deformities, cardiac anomaly (mitral valve prolapse), and ichthyosis.
  • Histopathology revealed a collagen hamartoma beneath the Becker's nevus.
  • The patient exhibited numerous features beyond the typical Becker's nevus syndrome criteria.

Conclusions:

  • This case underscores the wide phenotypic variability of Becker's nevus syndrome.
  • The extensive systemic involvement in this patient broadens the understanding of potential associated conditions.
  • Early recognition and comprehensive evaluation are crucial for managing patients with complex Becker's nevus syndrome.