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Mixed Reality Assisted Radical Endoscopic Thyroidectomy
Published on: January 31, 2025
Hypothyroidism after radiotherapy for primary thyroid lymphoma
Naoya Ishibashi1, Toshiya Maebayashi2, Takuya Aizawa2
1Department of Radiology, Nihon University School of Medicine, Itabashi-ku, Tokyo, Japan ishibashi.naoya@nihon-u.ac.jp.
Background:
Thyroid lymphoma is rare, with no standard therapeutic protocol. Radiotherapy is often employed.
Patients And Methods:
Nine patients who had received radiotherapy for thyroid lymphoma in our Institute, from September 2005 to August 2013, were reviewed for hypothyroidism. The median radiation dose was 40 Gy. Thyroid-stimulating hormone (TSH) levels were measured before and after radiotherapy, and hypothyroidism was defined as a TSH level exceeding 10 mIU/l. Peak TSH was defined as the highest TSH level during the follow-up period.
Results:
The complete response rate was 77.8%, and the 5-year overall survival rate was 74.1%. The median time-to-peak TSH was 162.5 days after the start of radiotherapy. Hypothyroidism was diagnosed in three (37.5%) out of eight patients without thyroidectomy.
Conclusion:
Hypothyroidism is a frequent complication of radiotherapy for thyroid lymphoma.
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