Misleading hepatitis B testing in the setting of intravenous immunoglobulin
Christelle M Ilboudo1, Erin M Guest2, Angela M Ferguson3
1Children's Mercy Hospitals and Clinics, Division of Infectious Diseases and University of Missouri-Kansas City School of Medicine, Kansas City, MO, 64108, USA.
Abstract:
Intravenous immunoglobulin (IVIG) is commonly used for a wide range of diagnoses, by multiple pediatric subspecialists. We report two cases of hepatitis B screening results post IVIG infusion, where positive anti-Hepatitis B core antigen serology tests indicated possible occult hepatitis infection, leading to a delay in care. However, serial antibody testing showed results consistent with the passive transfer of antibodies.
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