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Updated: Apr 26, 2026

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Published on: February 3, 2023
Spectrophotometric method for estimation of bisoprolol fumarate in tablets
Unlabelled:
Bisoprolol fumarate is prescribed for the treatment of hypertension and angina pectoris.
Aim:
The purpose of this study was to develop a simple, sensitive, accurate, and reproducible method for estimation of bisoprolol fumarate in tablets.
Material And Methods:
The proposed method was based on a yellow colored complex formed with tropaeolin 00, extractable in dichloromethane with maximum absorbance at 412 nm. The method was validated statistically.
Results:
The linearity domain was observed in the concentration of 5-30 microg/ml. The recovery studies confirmed the accuracy of the proposed method.
Conclusions:
The proposed method can be applied for the routine analysis of bisoprolol from formulations.
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