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Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
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Cough in asthma triggered by reflux episodes.
Delaware Medical Journal
|August 2, 2014
Summary
Gastroesophageal reflux, both acid and non-acid, frequently precedes cough in childhood asthma. Evaluating reflux is crucial for managing difficult pediatric asthma cases.
Area of Science:
- Pediatric Pulmonology
- Gastroenterology
- Allergy and Immunology
Background:
- Asthma in children is a chronic respiratory condition often associated with cough.
- Gastroesophageal reflux disease (GERD) is a potential extra-esophageal trigger for chronic cough and asthma exacerbations.
- Identifying specific reflux patterns preceding cough is essential for targeted management.
Purpose of the Study:
- To investigate the temporal relationship between gastroesophageal reflux episodes and cough in children with asthma.
- To differentiate between acid and non-acid reflux events as potential triggers for cough.
Main Methods:
- Utilized combined esophageal pH and impedance monitoring to detect reflux episodes.
- Monitored concurrent cough events in pediatric asthma patients.
- Analyzed the timing of reflux events in relation to cough occurrences.
Main Results:
- Both acid and non-acid reflux episodes were frequently detected immediately preceding cough in children with asthma.
- Combined pH and impedance monitoring proved effective in identifying these reflux events.
- A significant association was observed between reflux episodes and subsequent cough.
Conclusions:
- Gastroesophageal reflux, encompassing both acid and non-acid types, is a common immediate precursor to cough in pediatric asthma.
- Reflux should be considered and evaluated as a significant trigger in children with difficult-to-manage asthma.
- Combined pH and impedance monitoring offers valuable insights into the reflux-cough relationship in this population.
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