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Updated: Aug 15, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
Effectiveness of pH measurements in predicting feeding tube placement
N Metheny1, P Williams, L Wiersema
1Saint Louis University Medical Center, Missouri.
Insights
Gastric pH testing effectively distinguishes feeding tube placement. Aspirate pH values reliably differentiate gastric from intestinal or respiratory placement, enhancing patient safety.
Area of Science:
- Clinical Medicine
- Gastroenterology
- Critical Care Medicine
Background:
- Accurate feeding tube placement is crucial for patient safety and effective nutrition delivery.
- Misplacement of nasogastric (NG) and nasointestinal (NI) tubes can lead to serious complications.
- Distinguishing between gastric, intestinal, and respiratory placement is essential.
Purpose of the Study:
- To evaluate the efficacy of aspirate pH testing in differentiating feeding tube placement.
- To compare pH values of aspirates from gastric, intestinal, and respiratory locations.
- To determine the clinical utility of pH measurements for confirming tube position.
Main Methods:
- A clinical study involving 181 adult subjects with small-bore nasogastric or nasointestinal tubes.
- Collection of aspirate samples for pH measurement using pH-paper concurrently with X-rays.
- pH readings were taken at initial placement and after 1-2 days of tube feedings.
Main Results:
- pH values effectively differentiated gastric from intestinal placement (p < .0001).
- 81% of nasogastric aspirates showed pH 1-4, while 88% of nasointestinal aspirates had pH ≥ 6.
- An aspirate from a tube in the lung exhibited an alkaline pH.
Conclusions:
- Aspirate pH testing is a valuable, non-invasive method for verifying feeding tube placement.
- pH measurements can reliably distinguish gastric from intestinal placement.
- This technique can help prevent complications associated with incorrect tube positioning.
Abstract:
The extent to which pH values of aspirates from feeding tubes could be used to differentiate between (a) gastric and intestinal placement, and (b) gastric and respiratory placement were determined in a clinical study. The sample consisted of 181 adult subjects, 94 with small-bore nasogastric tubes and 87 with nasointestinal tubes. Data were collected at the time of initial tube placement and again, when possible, after one or two days of tube feedings. Using color coded pH-paper, a total of 247 readings were made concurrently with x-rays to determine feeding tube position. Findings indicated that pH readings were often effective in differentiating between gastric and intestinal placement (p less than .0001). For example, approximately 81% of the aspirates from nasogastric tubes had pH values ranging from 1 through 4, while almost 88% of the aspirates from nasointestinal tubes had pH values of 6 or greater. Only one aspirate from a tube inadvertently placed in the lung was tested; as expected it had an alkaline pH.
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