Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.0K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.0K
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

466
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
466
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.6K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.6K
Glaucoma: Overview01:25

Glaucoma: Overview

1.7K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.7K
Diabetic Retinopathy01:27

Diabetic Retinopathy

48
DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
48
Venous Return01:04

Venous Return

12.7K
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system...
12.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Multi-Organ Dysfunction in Neonatal Hypoxic Ischemic Encephalopathy and Brain Magnetic Resonance Imaging Outcomes.

Pediatric neurology·2026
Same author

Validation of Automated Software for Guttae Quantification in Fuchs Endothelial Corneal Dystrophy.

Translational vision science & technology·2026
Same author

Predicting Loss of Ambulation in Limb Girdle Muscular Dystrophy R9.

Annals of clinical and translational neurology·2026
Same author

ACT for postsurgical pain and dysfunction in at-risk veterans: Multisite, double-blind, cluster RCT.

Journal of psychosomatic research·2025
Same author

The significant impact of the distal ureteral diameter ratio as predictor of breakthrough urinary tract infections in children with vesicoureteral reflux.

Journal of pediatric urology·2025
Same author

Outcome Disparities Between Rural and Urban Infants with Single-Ventricle Heart Disease.

The Journal of pediatrics·2025

Related Experiment Video

Updated: Apr 26, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

2.7K

Fundus changes in central retinal vein occlusion.

Sohan Singh Hayreh1, M Bridget Zimmerman

  • 1*Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa; and †Department of Biostatistics, College of Public Health, University of Iowa, Iowa City, Iowa.

Retina (Philadelphia, Pa.)
|August 2, 2014
PubMed
Summary

Central retinal vein occlusion (CRVO) shows distinct retinal and optic disk changes. Ischemic CRVO presents with more severe, longer-lasting findings than nonischemic CRVO.

More Related Videos

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

Published on: November 20, 2016

8.3K
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
05:14

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Published on: August 11, 2023

1.7K

Related Experiment Videos

Last Updated: Apr 26, 2026

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability
07:23

Optimization of the Retinal Vein Occlusion Mouse Model to Limit Variability

Published on: August 6, 2021

2.7K
The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy rNAION

Published on: November 20, 2016

8.3K
Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization
05:14

Author Spotlight: Overcoming Anti-VEGF Resistance Through Advanced Vascular Morphology Assessment in Choroidal Neovascularization

Published on: August 11, 2023

1.7K

Area of Science:

  • Ophthalmology
  • Retinal Vascular Diseases

Background:

  • Central Retinal Vein Occlusion (CRVO) is a significant cause of vision loss.
  • Understanding the differences between ischemic (I-CRVO) and nonischemic (NI-CRVO) subtypes is crucial for patient management.

Purpose of the Study:

  • To systematically investigate and compare the retinal and optic disk changes in CRVO.
  • To elucidate the natural history of fundus findings in both I-CRVO and NI-CRVO.

Main Methods:

  • A cohort of 562 patients with CRVO was evaluated.
  • Ophthalmic examinations included visual acuity, visual fields, funduscopy, and fluorescein angiography.
  • Patients were classified into nonischemic (NI-CRVO) and ischemic (I-CRVO) groups.

Main Results:

  • Ischemic CRVO exhibited more severe initial hemorrhages, optic disk edema, and macular edema compared to NI-CRVO.
  • I-CRVO showed a higher incidence of macular degeneration, serous detachment, and perivenous sheathing.
  • Fluorescein angiography revealed greater capillary leakage, dilatation, and obliteration in I-CRVO.
  • Resolution times for fundus findings were significantly longer in I-CRVO.

Conclusions:

  • The characteristics and natural history of fundus findings differ significantly between ischemic and nonischemic CRVO.
  • These distinctions highlight the importance of classifying CRVO subtypes for prognosis and treatment.