Related Experiment Video
Updated: Apr 26, 2026
08:01
Rapid Scan Electron Paramagnetic Resonance Opens New Avenues for Imaging Physiologically Important Parameters In Vivo
Published on: September 26, 2016
8.8K
A high-frequency electron paramagnetic resonance spectrometer for multi-dimensional, multi-frequency, and multi-phase
F H Cho1, V Stepanov2, S Takahashi2
1Department of Physics, University of Southern California, Los Angeles, California 90089, USA.
The Review of Scientific Instruments
|August 3, 2014
Summary
We developed new instrumentation for high-frequency Electron Paramagnetic Resonance (EPR) and Electron-Electron Double Resonance (PELDOR) spectroscopy. This system enables advanced studies of electron spin systems in solids.
Area of Science:
- Spectroscopy
- Quantum Sensing
- Materials Science
Background:
- Electron Paramagnetic Resonance (EPR) and Electron-Electron Double Resonance (PELDOR) are powerful techniques for studying unpaired electrons.
- High-frequency EPR and PELDOR offer enhanced sensitivity and spectral resolution.
- Advanced instrumentation is crucial for pushing the boundaries of these spectroscopic methods.
Purpose of the Study:
- To describe the design and performance of novel instrumentation for high-frequency EPR and PELDOR spectroscopy.
- To demonstrate the capabilities of the new spectrometer in advanced EPR and PELDOR experiments.
- To highlight the utility of the instrumentation for probing spin systems in insulating materials.
Main Methods:
- Development of a spectrometer operating at 107-120 GHz and 215-240 GHz with a 0-12.1 T superconducting magnet.
- Integration of a high-power solid-state source, quasioptical system, phase-sensitive detection, and a (4)He cryostat.
- Implementation of multi-frequency continuous-wave EPR and pulsed EPR measurements with nanosecond pulse durations.
Main Results:
- Detailed description of the spectrometer's design and pulsed EPR sensitivity.
- Successful application of the instrumentation in PELDOR spectroscopy to investigate correlations in insulating electronic spin systems.
- Demonstration of dynamical decoupling techniques to extend electron spin coherence in solid-state systems.
Conclusions:
- The developed high-frequency EPR and PELDOR instrumentation provides a versatile platform for advanced spin spectroscopy.
- The system enables sensitive probing of spin correlations and spin coherence in challenging solid-state materials.
- This instrumentation opens new avenues for research in quantum sensing and materials science.
Related Concept Videos
01:17NMR Spectrometers: Radiofrequency Pulses and Pulse Sequences
1.8K
A pulse is a short burst of radio waves distributed over a range of frequencies that simultaneously excites all the nuclei in the sample. Upon passing a radio frequency pulse along the x-axis, the nuclei absorb energy corresponding to their Larmor frequencies and achieve resonance. This shifts the net magnetization vector from the z-axis toward the transverse plane. This angle of rotation of the magnetization vector, or the flip angle, is proportional to the duration and intensity of the pulse.
1.8K
01:17Electron Paramagnetic Resonance (EPR) Spectroscopy: Organic Radicals
2.5K
Ideally, an unpaired electron shows a single peak in the EPR spectrum due to the transition between the two spin energy states. However, coupling interactions can occur between the spins of the unpaired electron and any neighboring spin-active nuclei. This hyperfine coupling results in hyperfine splitting, where the EPR signal is split into multiplets. The signals split into 2nI + 1 peaks, where n is the number of equivalent nuclei and I is the nuclear spin. These splitting patterns provide...
2.5K
01:20NMR Spectrometers: Overview
2.0K
NMR spectrometers consist of a strong magnet, a radiofrequency transmitter, and a detector attached to a computer console for recording spectra of samples containing NMR-active nuclei. In first-generation NMR instruments called continuous-wave spectrometers, the resonance frequencies of the nuclei are determined by frequency-sweep or field-sweep methods. The magnetic field strength is fixed and the rf signal is swept in the former, while the radiofrequency signal is fixed and the magnetic field...
2.0K
01:26Inductively Coupled Plasma Atomic Emission Spectroscopy: Instrumentation
1.1K
Inductively coupled plasma (ICP) is the common plasma source used in atomic emission spectroscopy (AES), a technique that detects and analyzes various elements in a sample. This method is often called inductively coupled plasma atomic emission spectroscopy (ICP-AES).
There are three main types of inductively coupled plasma atomic emission spectroscopy (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
There are three main types of inductively coupled plasma atomic emission spectroscopy (ICP-AES) instruments: sequential, simultaneous multichannel, and Fourier transform instruments, with the latter being less commonly used....
1.1K
01:12Double Resonance Techniques: Overview
868
Double resonance techniques in Nuclear Magnetic Resonance (NMR) spectroscopy involve the simultaneous application of two different frequencies or radiofrequency pulses to manipulate and observe two distinct nuclear spins. One important application of double resonance is spin decoupling, which selectively suppresses coupling with one type of nucleus while observing the NMR signal from another nucleus, simplifying the spectrum and enhancing resolution.
Spin decoupling is usually achieved by...
Spin decoupling is usually achieved by...
868
01:14NMR Spectrometers: Resolution and Error Correction
991
When magnetic nuclei in a sample achieve resonance and undergo relaxation, the signal detected in NMR is an approximately exponential free induction decay. Fourier transform of an exponential decay yields a Lorentzian peak in the frequency domain. Lorentzian peaks in an NMR spectrum are defined by their amplitude, full width at half maximum, and position, where the peak width is governed by the spin-spin relaxation time alone. In real experiments, however, the applied magnetic field is rendered...
991