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Updated: Apr 26, 2026

Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
Sleep apnea ABCs: airway, breathing, circulation
1Director, Sleep Disorders Research, Cleveland Clinic; Associate Professor of Medicine, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH mehrar@ccf.org.
Obstructive sleep apnea (OSA) is common and serious, but often missed. Early diagnosis and continuous positive airway pressure (CPAP) treatment can prevent severe health issues like heart disease and stroke.
Area of Science:
- Sleep Medicine
- Cardiology
- Pulmonology
Background:
- Obstructive sleep apnea (OSA) is a prevalent yet underdiagnosed condition.
- Untreated OSA is linked to severe health consequences, including cardiovascular disease, stroke, and mortality.
- Early identification and management are crucial for patient outcomes.
Purpose of the Study:
- To highlight the importance of recognizing obstructive sleep apnea.
- To outline diagnostic pathways and treatment options for OSA.
- To emphasize the role of continuous positive airway pressure (CPAP) in managing OSA.
Main Methods:
- Utilizing simple clinical assessments to identify patients at risk for OSA.
- Recommending polysomnography for definitive diagnosis.
- Reviewing the efficacy of continuous positive airway pressure (CPAP) therapy.
Main Results:
- Clinical assessments can effectively screen for OSA.
- CPAP therapy significantly improves OSA symptoms and reduces associated risks.
- Patient education and adherence support enhance treatment success.
Conclusions:
- OSA requires greater clinical recognition due to its significant health impact.
- CPAP is the primary treatment, with alternatives available for non-responders.
- Effective patient management strategies are key to successful OSA treatment.
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