Related Experiment Video
Updated: Apr 26, 2026

Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
High surgical burden for infants with severe chronic lung disease (sCLD)
Theresa R Grover1, Beverly S Brozanski2, James Barry1
1University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
Insights
Most infants with severe chronic lung disease (sCLD) undergo multiple surgical procedures during NICU stays. Common operations include gastrostomy and tracheostomy, with varied timing and coordination.
Area of Science:
- Neonatal surgery
- Pediatric surgery
- Critical care medicine
Background:
- Severe chronic lung disease (sCLD) in infants often necessitates surgical interventions.
- The spectrum and frequency of surgical procedures for sCLD infants are not well-defined.
Purpose of the Study:
- To determine the frequency, types, and timing of surgical procedures in hospitalized infants with sCLD.
- To characterize the scope of operative interventions for this vulnerable population.
Main Methods:
- Utilized the Children's Hospital Neonatal Database (CHND) to identify infants with sCLD.
- Analyzed data from 24 children's hospital Neonatal Intensive Care Units (NICUs) over a 16-month period.
Main Results:
- 71% of 556 sCLD infants received at least one surgical procedure during NICU hospitalization, averaging 3 operations per infant.
- Most common procedures included gastrostomy (24%), fundoplication (11%), herniorrhaphy (13%), and tracheostomy (12%).
- Timing of gastrostomy and tracheostomy insertions varied, with concurrent placement in only 33% of infants receiving both.
Conclusions:
- A significant majority of infants with sCLD undergo multiple surgical procedures in NICUs.
- Further research is needed on the timing, coordination, and outcomes of these surgical interventions.
Background/Purpose:
Infants with severe chronic lung disease (sCLD) may require surgical procedures to manage their medical problems; however, the scope of these interventions is undefined. The purpose of this study was to characterize the frequency, type, and timing of operative interventions performed in hospitalized infants with sCLD.
Methods:
The Children's Hospital Neonatal Database was used to identify infants with sCLD from 24 children's hospital's NICUs hospitalized over a recent 16-month period.
Results:
556 infants were diagnosed with sCLD; less than 3% of infants had operations prior to referral and 30% were referred for surgical evaluation. In contrast, 71% of all sCLD infants received ≥1 surgical procedure during the CHND NICU hospitalization, with a mean of 3 operations performed per infant. Gastrostomy insertion (24%), fundoplication (11%), herniorrhaphy (13%), and tracheostomy placement (12%) were the most commonly performed operations. The timing of gastrostomy (PMA 48±10 wk) and tracheostomy (PMA 47±7 wk) insertions varied, and for infants who received both devices, only 33% were inserted concurrently (13/40 infants).
Conclusions:
A striking majority of infants with sCLD received multiple surgical procedures during hospitalizations at participating NICUs. Further work regarding the timing, coordination, perioperative complications, and clinical outcomes for these infants is warranted.
More Related Videos
06:15Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus
Published on: March 6, 2019
08:58Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs
Published on: October 31, 2025
Related Concept Videos
Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features
Pulmonary Cycle: Exhalation
Breathing
Chronic Obstructive Pulmonary Disease I: Introduction
Chronic Obstructive Pulmonary Disease
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease II: Emphysema