Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Macroscopic Convective Fluid Flows Arising From Binding of Ions and Small Molecules to Proteins.

Small (Weinheim an der Bergstrasse, Germany)·2026
Same author

Emergent Nonlinearity in Active Molecular Chemotaxis.

ACS nano·2026
Same author

Chemotaxis of ATPase-Powered Nanoparticles up Extra- and Intracellular ATP Gradients.

Nano letters·2026
Same author

Nonequilibrium surfactant partitioning into microdroplets generates local phase inversion conditions and interfacial instability.

Soft matter·2026
Same author

Droplets as Cell Models: Chemical Gradient-Induced Directional Filopodia Formation.

Journal of the American Chemical Society·2025
Same author

A roadmap for next-generation nanomotors.

Nature nanotechnology·2025

Related Experiment Video

Updated: Apr 26, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.2K

Self-powered glucose-responsive micropumps.

Hua Zhang1, Wentao Duan, Mengqian Lu

  • 1Department of Chemistry and ‡Department of Engineering Science and Mechanics, The Pennsylvania State University , University Park, Pennsylvania 16802, United States.

ACS Nano
|August 6, 2014
PubMed
Summary
This summary is machine-generated.

A novel self-powered micropump utilizes boronate chemistry to create fluid flow triggered by glucose. Pumping speed directly correlates with glucose concentration, offering a new method for glucose detection.

More Related Videos

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device
07:55

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device

Published on: January 26, 2010

11.3K
Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level
11:49

Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level

Published on: November 17, 2013

8.7K

Related Experiment Videos

Last Updated: Apr 26, 2026

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid
06:21

Osmotic Minipump Implantation for Increasing Glucose Concentration in Mouse Cerebrospinal Fluid

Published on: April 7, 2023

2.2K
A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device
07:55

A Multi-Parametric Islet Perifusion System within a Microfluidic Perifusion Device

Published on: January 26, 2010

11.3K
Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level
11:49

Quantitative and Temporal Control of Oxygen Microenvironment at the Single Islet Level

Published on: November 17, 2013

8.7K

Area of Science:

  • Polymer Science
  • Chemical Engineering
  • Biomedical Devices

Background:

  • Developing self-powered microfluidic devices is crucial for portable diagnostics.
  • Boronate chemistry offers unique responsive properties for chemical sensing applications.

Purpose of the Study:

  • To describe a self-powered polymeric micropump.
  • To investigate its performance based on boronate chemistry and glucose concentration.

Main Methods:

  • Fabrication of a polymeric micropump.
  • Utilizing boronate chemistry for glucose-triggered reactions.
  • Experimental verification and finite difference modeling of fluid dynamics.
  • Analysis of pumping velocity dependence on glucose concentration and chamber height.

Main Results:

  • The micropump operates autonomously, powered by the reaction exothermicity.
  • Pumping velocity is directly proportional to glucose concentration.
  • Fluid flow increases with chamber height.
  • Mannitol enhances pumping velocity more than glucose due to greater reaction exothermicity.

Conclusions:

  • A self-powered micropump based on boronate chemistry and glucose-induced buoyancy convection is demonstrated.
  • The device shows tunable fluid flow based on analyte concentration.
  • This technology has potential applications in glucose sensing and microfluidic control.