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Published on: November 11, 2022
[Chemical constituents of Cocculus orbiculatus var. mollis root]
Objective:
To study the chemical constituents in the root of Cocculus orbiculatus var. mollis.
Methods:
The compounds were isolated by silica gel chromatography, their structures were established by spectroscopic methods.
Results:
Eleven compounds were isolated and identified as wattisine A (I), O-methylcocsoline (II), (+) cocsoline (III), (+) cocsuline (IV), magnoflorine (V), sino-coculine (VI), isosinococuline (VII), (-) coclaurine (VIII), daucosterol (IX), beta-sitosterol (X) and 1-oleioyl-3-(9Z, 12Z-arachoyl) glycerol (XI).
Conclusion:
Compound I is isolated from this genus for the first time,and compound II - XI are isolated from this plant for the first time.
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