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Skeleton and Calcium Homeostasis

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Calcium is not only the most abundant mineral in bone but also the most abundant mineral in the human body. Calcium ions are needed for bone mineralization, tooth health, heart rate regulation and strength of contraction, blood coagulation, the contraction of smooth and skeletal muscle cells, and the regulation of nerve impulse conduction. The average calcium level in the blood is about 10 mg/dL. When the body cannot maintain this level, a person will experience hypo or hypercalcemia.
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The minerals contained in all of the food we consume are essential for our organ systems. However, certain essential minerals, such as calcium, phosphorus, magnesium, manganese, and fluoride, largely affect bone health.
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Role of Vitamins in Maintaining Bone Health01:25

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The growth and maintenance of bone are regulated by a combination of nutritional factors, including vitamins, such as vitamin A, B12, C, D, and K.
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In humans, electrolytes play a vital role in various physiological processes. Balancing electrolyte levels is essential for normal body functions; their imbalance can be life-threatening. The major electrolytes include sodium, potassium, chloride, calcium, phosphate, and bicarbonate. They are primarily involved in physiological processes, such as nerve signal transmission, membrane trafficking, muscle contraction, buffering body fluids, and balancing water levels in the body.
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Roles of Electrolytes: Calcium and Phosphate01:27

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Calcium and phosphate are essential electrolytes in the human body, with calcium being the most abundant mineral. Around 99% of the body's calcium is stored in the skeleton and teeth, forming a crystal lattice of mineral salts in combination with phosphates. Calcium plays crucial roles in various bodily functions such as blood clotting, neurotransmitter release, muscle tone maintenance, and nervous and muscle tissue excitability.
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Minerals01:26

Minerals

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Minerals are essential nutrients that the human body needs in small amounts to work properly. They play a vital role in many bodily functions, such as building strong bones and transmitting nerve impulses. Some minerals are needed for hormone production or to maintain a normal heartbeat. Major minerals include calcium, phosphorus, potassium, sulfur, sodium, chlorine, and magnesium, while trace minerals include iron, manganese, copper, iodine, zinc, cobalt, fluoride, and selenium.
 
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[Calcium--essential for everybody].

Grazyna Cichosz, Hanna Czeczot

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    |August 7, 2014
    PubMed
    Summary

    Optimal calcium intake is crucial for metabolic health, reducing risks of obesity, diabetes, and hypertension. Milk and dairy offer superior benefits over supplements due to added nutrients like vitamin D3.

    Area of Science:

    • Biochemistry
    • Human Physiology
    • Nutritional Science

    Context:

    • Calcium is a vital mineral regulating numerous metabolic processes in the human body.
    • Inadequate calcium intake is linked to increased body mass index, insulin resistance, type 2 diabetes, and osteoporosis.
    • Dietary calcium plays a role in managing hypertension by regulating blood vessel tension and sodium chloride activity.

    Purpose:

    • To elucidate the multifaceted roles of calcium in human health and disease prevention.
    • To compare the efficacy of calcium from milk and dairy products versus calcium supplements in managing diet-related illnesses.

    Summary:

    • Calcium is essential for metabolic regulation, with deficiency increasing risks for obesity, insulin resistance, and osteoporosis.
    • Adequate calcium intake helps mitigate hypertension and exhibits anticancerogenic properties by inhibiting cell hyperproliferation.

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  • Milk and dairy products, fortified with vitamin D3, CLA, proteins, and peptides, are more effective than calcium supplements for disease prevention, as supported by DASH diet research.
  • Impact:

    • Highlights the importance of dietary calcium for preventing metabolic disorders and chronic diseases.
    • Establishes milk and dairy as superior sources for calcium-related health benefits compared to supplements.
    • Provides evidence supporting the inclusion of dairy in dietary interventions for obesity, sclerosis, and hypertension.