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Updated: Apr 26, 2026

Developing a Rat Model for Bipolar Disorder
Published on: May 2, 2025
[Treatment of mania in adults]
Rasmus Wentzer Licht1, Sune Puggaard Vogt Straszek
1Enheden for Psykiatrisk Forskning, Aalborg Universitetshospital, Psykiatrien, Mølleparkvej 10, 9000 Aalborg. rasmus.licht@rn.dk.
Abstract:
Around 1% of the population will experience at least one episode of mania. Mania has negative social consequences, may lead to cognitive impairment and may even be lethal. Therefore, prompt and efficient medical action needs to be taken, not only addressing the acute symptoms but also the high risk of recurrence. Many well-documented antimanic drugs are at hand, and the database has been carefully outlined in recent guidelines, also addressing factors of importance in choosing among the options. The real challenge is dealing with non-response, where the database is extremely poor.
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