Related Experiment Video
Updated: Apr 26, 2026

Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
[Foetus from Varna with thanatophoric nanism type 2]
Unlabelled:
The first Bulgarian case of Thanatophoric nansim of foetus is presented, which is diagnosed by foetopathological autopsy, histological and postnatal X-ray examination.
Materials And Methods:
The foetus is a result of a still-birth. X-ray examination, autopsy of the foetus and microscopic examination were performed.
Results:
A female foetus, 28 gestation week, with micromelia, relative macrocrania with configuration "three leaved clover" type, shortened median cranial fossa, hypertrophy of temporal lobes of hemispheres with radial convolutions. Hypoplasia of the lungs. X-ray examination: Platispondylia, rectilinear femoral diaphysis, pelvis--square, lowered arches of acetabulums with lateral processes.
Conclusions:
The present examination establishes the importance of the application of foetopathological autopsy as a routine method in all spontaneous abortions and still-births in view of control of hypo- and achondrodysplasias.
Related Concept Videos
Teratogenicity
Meiosis I
Meiosis vs. Mitosis
Before the start of mitosis and meiosis I, the cell synthesizes DNA, resulting in two homologous copies of each chromosome. DNA synthesis is...
Lethal Alleles
Lucien Cuénot discovered lethal alleles in 1905 while studying the inheritance of coat color in mice. The agouti gene is responsible for the color of the coat in mice. This gene codes for an agouti-signaling protein, which is responsible for melanin distribution in mammals. The wild-type allele gives rise to gray-brown coat color in mice, while the mutant allele gives rise to yellow coat color. In addition to coat color, the agouti gene is associated with the yellow...
Neurulation
Nondisjunction

