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Updated: Apr 26, 2026

Three-Dimensional Imaging of the Vertebral Lymphatic Vasculature and Drainage using iDISCO+ and Light Sheet Fluorescence Microscopy
Published on: May 22, 2020
Imaging of adult leukodystrophies
Claudia Costa Leite1, Leandro Tavares Lucato2, Germana Titoneli Santos2
1Departamento de Radiologia, Faculdade de Medicina, Universidade de São Paulo, Sao Paulo, SP, Brazil.
Abstract:
Leukodystrophies are genetically determined white matter disorders. Even though leukodystrophies essentially affect children in early infancy and childhood, these disorders may affect adults. In adults, leukodystrophies may present a distinct clinical and imaging presentation other than those found in childhood. Clinical awareness of late-onset leukodystrophies should be increased as new therapies emerge. MRI is a useful tool to evaluate white matter disorders and some characteristics findings can help the diagnosis of leukodystrophies. This review article briefly describes the imaging characteristics of the most common adult leukodystrophies.
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