Related Experiment Video

Updated: Apr 26, 2026

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia
06:28

Author Spotlight: Investigating the Complex Immune Response Following Brain Ischemia

Published on: July 26, 2024

4.1K

Street-experienced peripheral B cells traffic to the brain

Daniel R Lu1, William H Robinson2

  • 1Division of Immunology and Rheumatology, Stanford University, Stanford, CA 94305, USA. Stanford Immunology Program, Stanford University School of Medicine, Stanford, CA 94305, USA.

Science Translational Medicine
|August 8, 2014
PubMed

Deep sequencing of immunoglobulin repertoires in multiple sclerosis patients reveals dysregulation of peripheral B cell immunity (Palanichamy et al. and Stern et al., this issue).

More Related Videos

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells09:35

Isolating Central Nervous System Tissues and Associated Meninges for the Downstream Analysis of Immune cells

Published on: May 19, 2020

10.2K
Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses09:55

Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses

Published on: February 3, 2022

6.7K

Related Concept Videos

B Cell Activation and Differentiation01:24

B Cell Activation and Differentiation

The adaptive immune response, a sophisticated defense mechanism, relies on the activation and differentiation of B lymphocytes, or B cells. These processes enable our bodies to mount a tailored response against specific pathogens such as bacteria, free virus particles, toxins, and parasites.
When naive B cells encounter a specific antigen that can bind to the B cell receptor (BCR) on their surface, they undergo sensitization to respond to the antigen's presence. Sensitization begins with...
14.3K
Cells of the Adaptive Immune Response01:23

Cells of the Adaptive Immune Response

The T and B lymphocytes of the adaptive immune system develop from common lymphoid progenitor cells in the bone marrow. These progenitors give rise to precursors that eventually develop into both T and B lymphocytes. As these precursors mature, they gain the ability to detect and respond to foreign antigens in the body, a process known as immunocompetence. Additionally, these precursors acquire self-tolerance, a process that ensures they do not react to self-antigens. This intricate system...
6.8K
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
17
The Blood-brain Barrier00:49

The Blood-brain Barrier

Overview
47.2K
Humoral Immune Responses01:36

Humoral Immune Responses

Overview
65.7K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
3.0K