Investigation on immunoglobulin fortification in preventing infections in the newborn

Observations in neonatal sepsis revealed that the IgG concentrations in septic newborns is significantly lower than in non septic infants. This condition lead the author to investigate the role of fortification of IgG in infants with intrapartum infections. For this purpose a prospective study was carried out, 35 newborn infants with intrapartum infections were treated with IgG Cutter 0.6 mg per Kg BW per week and 35 other infants with similar criteria served as control group. The result of the trial showed that IgG administration could help in prevention of minor infections.