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Updated: Apr 26, 2026

Methods for Detecting Cough and Airway Inflammation in Mice
Published on: August 2, 2024
Insights
Investigating chronic cough in children requires a thorough approach. This review outlines diagnostic strategies for persistent cough, focusing on history, physical exams, and targeted tests to find underlying causes.
Area of Science:
- Pediatric Pulmonology
- Clinical Diagnosis
- Respiratory Medicine
Background:
- Cough is a frequent reason for pediatric medical visits.
- Acute cough, often infection-related, typically resolves within 4 weeks.
- Prolonged cough (chronic) necessitates evaluation for diverse respiratory and non-respiratory conditions.
Purpose of the Study:
- To present an optimal diagnostic strategy for chronic cough in children.
- To guide clinicians in identifying the underlying causes of persistent pediatric cough.
Main Methods:
- Systematic review of diagnostic approaches for pediatric chronic cough.
- Emphasis on skillful patient history taking.
- Guidance on performing a thorough physical examination.
- Recommendations for selecting appropriate diagnostic tests.
Main Results:
- A structured diagnostic process is crucial for effective management.
- Key historical features and physical findings aid in differential diagnosis.
- Appropriate test selection minimizes unnecessary investigations.
Conclusions:
- A systematic approach combining history, physical exam, and judicious testing improves the diagnosis of chronic cough in children.
- Identifying the root cause is essential for effective treatment and management of pediatric respiratory conditions.
Abstract:
Cough is probably the most common cause of seeking medical care in pediatric practice. Most acute cough is caused by infection and usually resolves within less than 4 weeks. If it lasts longer, it is considered chronic and deserves investigation to identify the underlying cause, which can be almost any of a wide variety of illnesses of the respiratory tract and certain extrathoracic conditions. This review provides an optimal approach for diagnosis through a skillful history taking, physical examination, and selection of appropriate tests.
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