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Haemodynamics during dialysis and cognitive performance.

Dawn F Wolfgram1, Lily Sunio, Elisabeth Vogt

  • 1Section of Nephrology, Medicine Division, Clement J. Zablocki VA Medical Center, Milwaukee, WI, USA; Division of Nephrology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.

Nephrology (Carlton, Vic.)
|August 9, 2014
PubMed
Summary
This summary is machine-generated.

Dialysis patients face higher cognitive impairment risks. This study found no link between blood pressure changes during dialysis and cognitive function, though age and race were factors.

Keywords:
blood pressurescognitive impairmenthaemodialysishypotension

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Area of Science:

  • Nephrology
  • Neurology
  • Cardiovascular Science

Background:

  • Hemodialysis (HD) patients exhibit an elevated risk of cognitive impairment (CI).
  • Blood pressure (BP) fluctuations during HD may impact cerebral perfusion and cognitive function.

Purpose of the Study:

  • To investigate the relationship between blood pressure variability during hemodialysis and cognitive outcomes in patients aged 50 and older.

Main Methods:

  • 39 HD patients without dementia were assessed for cognitive impairment using a neurocognitive battery.
  • Blood pressure measurements from 12 dialysis sessions were collected.
  • Associations between cognitive impairment categories and BP fluctuation metrics were analyzed, adjusting for covariates.

Main Results:

  • No significant association was found between blood pressure fluctuation parameters (e.g., SBP drop, SBP < 90 mmHg) and cognitive performance.
  • Older age and non-Caucasian race were independently associated with reduced cognitive scores.

Conclusions:

  • This study found no cross-sectional association between blood pressure changes during hemodialysis and cognitive performance in the studied population.