Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Adaptive Physics-Aware Raman Baseline Correction with Machine Learning Predicted Parameters.

Analytical chemistry·2025

Same author

Pyridines in Photoelectrocyclization Reactions: The Effect of Substitution and Reaction Conditions on Pyridine Photoelectrocyclizations.

The Journal of organic chemistry·2025

Same author

Label-Free SERS Sensors for Real-Time Monitoring of Tyrosine Phosphorylation.

Analytical chemistry·2024

Same author

SERS Microsensors for the Study of pH Regulation in Cystic Fibrosis Patient-Derived Airway Cultures.

ACS sensors·2024

Same author

SERS microsensors for pH measurements in the lumen and ECM of stem cell derived human airway organoids.

Chemical communications (Cambridge, England)·2023

Same author

Automatic Cocrystal Detection by Raman Spectral Deconvolution-Based Novelty Analysis.

Analytical chemistry·2021

Search research articles

Related Experiment Video

Updated: Apr 26, 2026

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Published on: July 22, 2013

Ratiometric biological nanosensors.

Kate M Fisher¹, Colin J Campbell¹

¹*EaStCHEM School of Chemistry, University of Edinburgh, Edinburgh EH9 3JJ, U.K.

Biochemical Society Transactions

|August 12, 2014

Summary

Ratiometric nanosensors enable precise measurement of intracellular analytes, offering insights into cell function. This review highlights advances in these biological sensors for quantitative analysis of key cellular molecules.

Area of Science:

Biomedical Engineering
Cell Biology
Analytical Chemistry

Background:

Intracellular analyte measurement is crucial for understanding cellular processes.
Biological nanosensors reveal spatial and temporal analyte variations.
Ratiometric nanosensors provide quantitative concentration measurements.

Purpose of the Study:

To review recent advancements in ratiometric intracellular biological nanosensors.
To emphasize the utility of these nanosensors in measuring critical cell function analytes.

Main Methods:

Review of recent scientific literature on ratiometric nanosensors.
Focus on sensor design and application for intracellular analyte detection.

Main Results:

More Related Videos

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Related Experiment Videos

Last Updated: Apr 26, 2026

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Ratiometric Biosensors that Measure Mitochondrial Redox State and ATP in Living Yeast Cells

Published on: July 22, 2013

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Fluorescent Nanoparticles for the Measurement of Ion Concentration in Biological Systems

Published on: July 4, 2011

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Fabrication of Carbon Nanotube High-Frequency Nanoelectronic Biosensor for Sensing in High Ionic Strength Solutions

Published on: July 22, 2013

Ratiometric nanosensors offer enhanced precision and quantitative capabilities.
Significant progress has been made in developing nanosensors for various intracellular analytes.
These sensors are vital tools for studying cell signaling and metabolism.

Conclusions:

Ratiometric intracellular biological nanosensors represent a significant technological advance.
Their application is key to deepening our understanding of cellular functions and dysfunctions.
Future developments promise even more sophisticated analyte detection within living cells.